Product Name: Polyvinylpyrrolidone
Chemical Formula: (C6H9NO)n
CAS Number: 9003-39-8
Common Names: PVP, povidone
Manufacturer/Supplier: Multiple global chemical suppliers
Recommended Use: Pharmaceutical binder, cosmetic stabilizer, adhesive, food additive
Contact Information: Local office of your supplier or manufacturer, emergency contact provided on shipping documentation
Classification: Not classified as hazardous per GHS
Signal Word: None required
Hazard Statements: Dust from large quantities can cause mild eye, skin, and respiratory irritation
Precautionary Statements: Avoid inhalation of dust, use proper personal protective equipment in bulk handling areas
Potential Health Effects: Eyes may become irritated if exposed to dust; skin contact may cause dryness; inhalation of fine powder could lead to respiratory irritation or coughing
Environmental Hazards: Low risk to environment, not expected to bioaccumulate
Component: Polyvinylpyrrolidone
Chemical Identification: Homopolymer of 1-vinyl-2-pyrrolidone
Concentration: 100% (commercial forms may have trace impurities, levels below hazardous thresholds)
Inhalation: Move exposed individual to fresh air. Seek medical advice if discomfort persists. Symptoms usually mild and resolve quickly with rest.
Skin Contact: Wash area thoroughly with soap and water. Remove contaminated clothing. Most exposures do not require medical attention.
Eye Contact: Flush with plenty of water for at least 15 minutes, holding eyelids open. Seek medical evaluation if irritation continues.
Ingestion: Rinse mouth. Give water to drink. Ingestion of small amounts considered low risk. Seek advice for large ingestions or symptoms.
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide.
Specific Hazards: Burns and decomposes at high temperatures, possible production of carbon oxides and nitrogen oxides
Special Protective Equipment For Firefighters: Full protective clothing and self-contained breathing apparatus recommended. Avoid inhaling smoke or decomposition gases.
Explosion Data: Dust may form explosive mixtures with air in confined spaces.
Personal Precautions: Avoid generating dust. Ensure adequate ventilation. Wear dust mask, gloves, and safety eyewear.
Spill Cleanup: Sweep up and collect in appropriate containers. Dispose of according to local regulations. Wash spill site after removal.
Environmental Precautions: Prevent entry into drains and watercourses. In large spills, recover for reuse or disposal.
Handling: Use in well-ventilated areas. Minimize dust creation. Handle with clean, dry gloves and protective eyewear if needed.
Storage Conditions: Store in tightly closed containers, cool and dry. Keep away from strong oxidizers and direct sunlight.
Incompatible Materials: Strong oxidizing agents, strong acids.
General Hygiene: Wash hands after handling, avoid eating or drinking in use areas.
Occupational Exposure Limit: No established limits for PVP; treat exposure control as with nuisance dust (10 mg/m³ for inhalable dust, 3 mg/m³ for respirable dust)
Engineering Controls: Local exhaust recommended for dusty operations
Personal Protection: Dust mask or respirator recommended for large-scale work. Safety goggles and gloves should be used. Standard work clothing sufficient for routine tasks.
Hygiene Measures: Wash hands and face after working with PVP; launder clothing before reuse
Appearance: White to off-white powder or flakes, odorless
Molecular Weight: Varies by grade and application, ranges from 10,000 to over 1,000,000 g/mol
Solubility: Soluble in water, alcohols, some organic solvents
Melting Point: Decomposes above 150°C
Boiling Point: Not applicable (solid polymer)
Vapor Pressure: Negligible
Density: About 1.1 – 1.3 g/cm³
pH: 3 to 5 (10% aqueous solution)
Other Properties: Forms clear solutions in water, hygroscopic (absorbs moisture from air), nonvolatile
Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: No dangerous polymerization
Conditions to Avoid: Excessive heat, open flame, strong oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides produced when burned or heated strongly
Incompatible Materials: Strong oxidizing agents, strong acids
Acute Toxicity: Low oral and dermal toxicity in animal studies
Chronic Toxicity: Long-term exposure not linked to major health effects in research studies, though chronic inhalation of dust may cause mild respiratory symptoms
Sensitization: Rare mild skin sensitization detected in some individuals
Mutagenicity / Carcinogenicity / Reproductive Effects: No evidence found in scientific testing for mutagenic, carcinogenic, or reproductive risks
Target Organs: Eyes, skin, respiratory tract (via dust exposure)
Aquatic Toxicity: Low toxicity to aquatic life shown in studies
Persistence and Degradability: Slowly biodegradable, especially in soil or aquatic environments
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Soluble, can migrate in moist soils
Other Adverse Effects: No significant negative impacts reported from field use
Waste Disposal: Dispose of in accordance with national and local regulations. Not considered hazardous waste.
Container Disposal: Rinse containers thoroughly. Dispose or recycle per local procedures.
Special Precautions: Prevent dust release during disposal to protect air quality.
UN Number: Not regulated
Proper Shipping Name: Polyvinylpyrrolidone
Hazard Class: Not classified as hazardous for transportation
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precaution: Avoid dust formation, always transport in secure, sealed packaging to minimize spillage
International Inventories: Listed on TSCA (USA), EINECS/ELINCS (EU), AICS (Australia), DSL/NDSL (Canada), ENCS (Japan), PICCS (Philippines), and other national inventories
Workplace Regulations: Observe general workplace chemical safety regulations and access to Material Safety Data Sheet
Labelling Requirements: Not subject to hazardous labeling under GHS
Other Requirements: Food, pharmaceutical, and cosmetic uses may require compliance with industry-specific GMP, purity, and traceability rules as set by FDA, EFSA, or equivalent national authorities
