Product Name: Benzisothiazolinone
Other Names: 1,2-Benzisothiazolin-3-one
Chemical Formula: C7H5NOS
CAS Number: 2634-33-5
Recommended Use: Industrial biocide, preservative in paints, adhesives, cleaning agents
Supplier/Manufacturer: [Manufacturer contact information on physical label]
Emergency Phone: Refer to product label for emergency contact
Classification: Acute Toxicity (Oral) Category 4, Eye Damage/Irritation Category 1, Skin Sensitization Category 1
Hazard Pictograms: Exclamation mark, corrosion symbol
Signal Word: Danger
Hazard Statements: Harmful if swallowed. Causes serious eye damage. May cause an allergic skin reaction.
Precautionary Statements: Avoid skin and eye contact. Wear protective gloves, eye protection, and suitable clothing. Wash hands after handling. Do not eat, drink, or smoke when using the product.
Symptoms: Eye redness, pain, burns, skin irritation, allergic reactions, gastrointestinal discomfort after ingestion.
Chemical Name: 1,2-Benzisothiazolin-3-one
Concentration: Typically 10-20% in aqueous solution, up to 100% pure
CAS Number: 2634-33-5
Impurities: Low levels of other isothiazolinones may be present
Additives: Water or other stabilizers may be included dependent on formulation
Eye Contact: Immediately flush with clean water for at least 15 minutes; remove contact lenses if present; seek medical attention promptly.
Skin Contact: Wash with soap and water; remove contaminated clothing; get medical help if irritation persists.
Inhalation: Move affected person to fresh air; provide artificial respiration if not breathing; seek medical attention.
Ingestion: Rinse mouth thoroughly; do not induce vomiting; seek medical care at once; never give anything by mouth to an unconscious person.
Most Important Symptoms and Effects: Eye damage, skin allergy, stomach upset, respiratory distress in severe cases.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Media: Direct water jet on burning liquid can spread fire
Specific Hazards: May emit toxic fumes including nitrogen oxides, sulfur oxides, carbon oxides
Special Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus
Advice: Keep containers cool by spraying with water; prevent runoff into drains, surface, or ground water.
Personal Precautions: Use personal protection such as gloves, goggles, and chemical-resistant clothing; ventilate the area
Environmental Precautions: Prevent entry into waterways, drains, soil
Cleanup Methods: Contain spill, absorb with inert material like sand or earth, collect in covered containers for disposal
Decontamination: Wash area with plenty of water; air area out before reuse
Reporting: Notify authorities if larger quantities escape or if contamination of environment occurs
Handling: Wear appropriate PPE, avoid skin and eye contact, use only with adequate ventilation, never eat or drink near handling areas
Storage: Store in tightly sealed containers, keep in cool, dry, well-ventilated place, avoid direct sunlight, segregate from food and incompatible chemicals like strong oxidizers
Techniques: Rotation of stock recommended to minimize use of expired or degraded material.
Security: Restrict access to properly trained personnel, keep container labels visible and intact.
Occupational Exposure Limits: No specific national exposure limit established in most regions; follow internal guidelines or supplier recommendations
Engineering Controls: Use local exhaust ventilation, general room ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, protective clothing for full skin cover, suitable respiratory protection if ventilation insufficient
Hygiene Measures: Wash hands and face before breaks, after handling, and before eating or smoking, remove contaminated clothing promptly
Environmental Controls: Minimize airborne emissions, protect drains and environment
Appearance: Off-white to pale yellow crystalline powder or liquid in solution
Odor: Faint characteristic odor
Odor Threshold: Not well established
pH: 7-9 (in 1% aqueous solution)
Melting Point: 155–158 °C for pure solid
Boiling Point: Decomposes before boiling
Flash Point: >100°C
Solubility: Slightly soluble in water; more soluble in organic solvents
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.3 g/cm³
Viscosity: Not applicable for solid
Partition Coefficient (n-octanol/water): Log Kow around 0.6
Decomposition Temperature: Above 200°C
Explosion Properties: Not explosive
Oxidizing Properties: Not oxidizing
Reactivity: Stable under normal use and storage conditions
Chemical Stability: Stable in original container at ambient temperatures
Possibility of Hazardous Reactions: No hazardous polymerization
Conditions to Avoid: Excessive heat, freezing, exposure to acids or strong oxidizers
Incompatible Materials: Strong acids, strong oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon oxides on combustion or thermal decomposition
Acute Toxicity: LD50 (oral, rat): about 670 mg/kg; LD50 (dermal, rat): >2000 mg/kg
Skin Corrosion/Irritation: Can cause moderate skin irritation, can produce allergic contact dermatitis
Serious Eye Damage/Irritation: Causes severe irritation and potential irreversible damage
Respiratory Sensitization: Inhalation of mist may cause respiratory irritation, asthma-like symptoms rare but documented
Skin Sensitization: Sensitizer, prolonged or repeated contact increases risk
Germ Cell Mutagenicity: No evidence from standard tests
Carcinogenicity: Not classified as carcinogen by IARC, OSHA, or NTP
Reproductive Toxicity: No adverse effects reported at occupational exposures
Specific Target Organ Toxicity (Single/Repeated): No known significant effects
Aspiration Hazard: Not expected under normal conditions
Aquatic Toxicity: Very toxic to aquatic life with long-lasting effects; LC50 (fish, 96h): 1.6 mg/L; EC50 (daphnia, 48h): 0.13 mg/L
Persistence and Degradability: Not readily biodegradable in aquatic environment
Bioaccumulative Potential: Low potential for bioaccumulation (Log Kow ~0.6)
Mobility in Soil: Moderate mobility, risk to groundwater if large quantities are released
Other Adverse Effects: Toxic to algae and microorganisms; may disrupt wastewater treatment processes at high concentrations
Waste Treatment Methods: Collect and deliver to certified hazardous waste disposal facility; never release into environment
Disposal of Contaminated Packaging: Decontaminate containers before recycling, or dispose in accordance with local regulations
Sewage Disposal: Avoid discharge to drains or watercourses
Precaution: Consult local, regional, and national regulations for proper method; incineration preferred if compliant with regulations.
UN Number: 3077
UN Proper Shipping Name: Environmentally Hazardous Substance, Solid, N.O.S. (contains Benzisothiazolinone)
Transport Hazard Class: 9
Packing Group: III
Labels: Environmentally hazardous substance mark required
Marine Pollutant: Yes
Special Precautions: Prevent release, secure packaging during handling and transport, notify carrier of nature of cargo
EU Regulation: Classified and labeled according to CLP Regulation (EC) No 1272/2008; subject to REACH registration
US Regulation: Listed in TSCA inventory; SARA 311/312 hazard categories: Acute; not subject to OSHA PELs
Canada: Listed in Canada DSL/NDSL, considered hazardous under WHMIS 2015
Australia: Listed in AICS inventory
International: Subject to international transport regulations such as IMDG and IATA
Other Applicable Restrictions: Product use may be restricted or subject to authorization in certain biocidal or industrial applications—always consult local, state, and national regulations before purchase or use.
