Product Name: Climbazole
Chemical Formula: C15H17ClN2O2
CAS Number: 38083-17-9
Synonyms: 1-(4-Chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one
Intended Use: Used in personal care as an anti-fungal agent, common in shampoos and skin products
Supplier Details: Manufacturer and supplier name, address, contact phone, emergency number
Classification: Harmful if swallowed, causes skin and eye irritation, potential respiratory hazard if inhaled
GHS Signal Word: Warning
Hazard Statements: May cause skin irritation, may cause serious eye irritation, harmful to aquatic life with long-lasting effects
Pictograms: Exclamation mark, environmental hazard symbol
Precautionary Statements: Wash hands thoroughly after handling, avoid release to the environment, wear protective gloves, protective clothing, eye protection, and face protection
Substance: Climbazole
Concentration: 98–100% pure (technical grade), the remainder may include water or inert ingredients
Impurities: Traces of organic solvents, potential by-products from manufacturing synthesis
Molecular Weight: 292.76 g/mol
EC Number: 253-775-4
Inhalation: Move affected person to fresh air, keep comfortable, seek medical attention if symptoms persist
Skin Contact: Rinse immediately with soap and water, remove contaminated clothing, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, call a physician if irritation continues
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice promptly, give water only if conscious
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Unsuitable Media: Do not use direct water jet on burning material
Hazards from Combustion: Hydrogen chloride, nitrogen oxides, carbon monoxide, and carbon dioxide may be released
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective clothing
Special Procedures: Control run-off from fire-fighting to prevent entry to waterways; cool containers exposed to flames
Personal Precautions: Wear gloves, protective clothing, and safety goggles; avoid breathing dust
Environmental Precautions: Prevent entry into drains, water sources, or soil
Containment: Collect spilled material with non-combustible absorbents (sand, earth), transfer to a suitable container for disposal
Cleanup Methods: Clean spill area with water and detergent after material pickup, ventilate area well
Safe Handling: Use in well-ventilated spaces, keep container tightly closed, avoid skin and eye contact, do not breathe dust
Hygiene Measures: Wash hands, face, and exposed skin after handling, remove contaminated clothing
Storage Conditions: Store in cool, dry, and well-ventilated areas, keep away from incompatible materials such as strong oxidizers, acids, and bases
Packaging Materials: Use original containers or chemical-resistant, tightly sealed alternatives
Exposure Limits: No established occupational exposure limits; avoid generation of dust
Engineering Controls: Use local exhaust ventilation as needed to maintain airborne concentrations below permissible exposure levels
Respiratory Protection: Approved particulate respirators recommended for insufficient ventilation
Hand Protection: Chemical-resistant gloves such as nitrile or neoprene
Eye Protection: Safety goggles or face shield
Skin Protection: Lab coats, chemical protective clothing, closed footwear
Appearance: White to off-white crystalline powder
Odor: Faint, characteristic
pH: 3.0–4.0 (1% in water)
Melting Point: 96–100 °C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Slightly soluble in water, readily soluble in ethanol and acetone
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Approximately 2.9
Relative Density: Around 1.25 g/cm³
Flash Point: >180°C (closed cup)
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended storage conditions and usage
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hazardous Decomposition: Releases toxic fumes of hydrogen chloride, nitrogen oxides, carbon oxides when heated to decomposition
Polymerization: Does not occur
Conditions to Avoid: Excessive temperatures, direct sunlight, humidity
Acute Toxicity: Oral LD50 in rats is roughly 2000 mg/kg; may cause irritation to digestive tract
Skin Corrosion/Irritation: Causes moderate skin irritation with prolonged exposure
Serious Eye Damage/Irritation: Causes serious eye irritation, may result in redness or discomfort
Respiratory Sensitization: Dust may cause respiratory tract irritation
Chronic Effects: Possible allergic skin reaction on repeated contact, no known carcinogenicity
Mutagenicity: Testing shows no evidence for mutagenicity or genotoxicity at standard exposure levels
Aquatic Toxicity: Harmful to aquatic organisms, with long-lasting effects, LC50 fish (96 h): 3.6 mg/L, EC50 Daphnia: 2.5 mg/L
Persistence and Degradability: Biodegrades slowly in the environment
Bioaccumulative Potential: Moderate, based on partition coefficient
Mobility in Soil: Low mobility, binds to soil particles
Other Adverse Effects: Should not be released uncontrolled into natural waters
Waste Disposal Method: Dispose of contents and container according to local, regional, national, and international regulations
Hazardous Waste Code: Unlisted, but treat as hazardous due to aquatic toxicity
Disposal of Packaging: Rinse empty containers, offer for recycling if available, otherwise dispose as hazardous waste
UN Number: Not classified as hazardous for land, air, or sea transport currently
Proper Shipping Name: Climbazole or chemical, not otherwise specified
Transport Hazard Classes: Not regulated
Packing Group: Not regulated
Special Precautions: Avoid transport with incompatible substances, protect from moisture and high heat
Labelling: Must display appropriate hazard symbols and safety phrases as dictated per country legislation
Restrictions: Use in consumer products capped by EU Cosmetic Regulation (EC) No 1223/2009, maximum allowed concentration in finished cosmetic products stipulated
Inventory Status: Listed on EINECS, TSCA, DSL, AICS, and other major chemical inventories
Regulatory References: Subject to REACH registration requirements in Europe; reviewed under US EPA TSCA
Worker Protection Laws: Safety Data Sheet (SDS) required for workplace use, must comply with OSHA Hazard Communication Standard in the US
