Filim Chemical

Knowledge

Material Safety Data Sheet: Choline Chloride

Identification

Product Name: Choline Chloride
Chemical Formula: C5H14ClNO
CAS Number: 67-48-1
UN Number: Not assigned
EINECS Number: 200-655-4
Recommended Use: Animal feed additive, nutrient supplement, laboratory reagent
Supplier Details: Manufacturer contact information, including address, phone number, and emergency contact

Hazard Identification

Classification: Not classified as hazardous under GHS; may cause mild irritation to skin, eyes, and respiratory tract
Hazard Statements: Dust can irritate eyes and mucous membranes; inhalation may cause coughing
Precautionary Statements: Avoid breathing dust; use with adequate ventilation; wash hands after handling
Signal Word: None
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Irritation of respiratory system, redness, mild burning of eyes or skin, upset stomach if swallowed

Composition / Information on Ingredients

Substance: Choline Chloride
Chemical Name: 2-hydroxy-N,N,N-trimethylethanaminium chloride
Purity: Typically >98% by weight
Other Components: Water (in hydrated forms), trace colorants if formulated
Hazardous Components: None present at hazardous concentrations per OSHA guidelines

First Aid Measures

General Advice: Remove affected person from exposure; seek medical attention for persistent symptoms
Inhalation: Move to fresh air; consult doctor if irritation persists
Skin Contact: Rinse thoroughly with soap and water
Eye Contact: Flush eyes with water for at least 15 minutes; consult ophthalmologist if irritation continues
Ingestion: Rinse mouth; seek medical advice if large amount is swallowed or symptoms develop
Note to Physicians: Treat symptomatically; no specific antidote documented

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical powder, carbon dioxide, or foam
Specific Hazards: Material can decompose at high temperatures, releasing hazardous gases such as trimethylamine and hydrochloric acid
Protective Equipment: Wear full protective gear and self-contained breathing apparatus
Advice for Firefighters: Prevent water runoff from contaminating surface water or groundwater; isolate area if safe to do so
Thermal Decomposition Products: Chlorine compounds, nitrogen oxides, carbon oxides

Accidental Release Measures

Personal Precautions: Wear appropriate respiratory protection, gloves, and goggles
Environmental Precautions: Prevent release to surface water, sewer, or soil
Cleanup Methods: Sweep up and place in suitable, labeled containers; avoid raising dust; ventilate area
Disposal: Collect for disposal per local regulations
Spill Response: Wash affected area with soap and water after cleaning

Handling and Storage

Handling: Minimize dust formation; avoid contact with skin, eyes, and clothing; use only in well-ventilated areas
Storage Conditions: Store in dry, well-ventilated location; keep containers tightly closed; protect from moisture, direct sunlight, and incompatible chemicals
Incompatibilities: Strong oxidizers, strong bases
Special Precautions: Use antistatic measures; always transfer using grounded equipment if large quantities handled
Storage Temperature: Ambient temperatures, away from sources of heat and ignition

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established for choline chloride
Engineering Controls: Local exhaust ventilation in areas where dust may be generated
Personal Protective Equipment: Safety glasses or goggles; chemical-resistant gloves; dust mask or respirator in dusty environments; laboratory coats or work clothing
Hygiene Measures: Wash hands after handling; do not eat, drink, or smoke near product

Physical and Chemical Properties

Appearance: White to off-white crystalline powder or hygroscopic flakes
Odor: Mild amine odor
Molecular Weight: 139.62 g/mol
Melting Point: 302°C (with decomposition)
Boiling Point: Not applicable (decomposes)
Solubility: Very soluble in water, alcohol; insoluble in most non-polar solvents
pH (solution): 6.8–8.0 (10% aqueous solution)
Vapor Pressure: Not applicable
Density: About 0.6–0.7 g/cm³ (powder)
Partition Coefficient (n-octanol/water): Log Kow: -3.7
Flash Point: Not applicable
Auto-ignition Temperature: Data not available

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: No known dangerous reactions under proper use
Conditions to Avoid: Excessive heat, open flames, moisture
Incompatible Materials: Strong oxidizing agents, strong bases
Hazardous Decomposition Products: Trimethylamine, hydrochloric acid, carbon monoxide, nitrogen oxides
Polymerization: Will not occur

Toxicological Information

Acute Toxicity (Oral LD50): Rat: >3,000 mg/kg
Routes of Exposure: Inhalation, skin, eye, ingestion
Potential Health Effects: Mildly irritating to eyes, skin, and respiratory tract; large oral doses may cause gastrointestinal distress
Skin Irritation: Low
Eye Irritation: Moderate but reversible
Chronic Effects: No evidence for long-term toxicity, carcinogenicity, mutagenicity, or reproductive toxicity in humans or animals at occupational exposure levels
Sensitization: Not reported

Ecological Information

Aquatic Toxicity: Not expected to be hazardous, but high concentrations can cause localized disruptions in aquatic systems
Persistence and Degradability: Rapidly biodegradable in water and soil
Bioaccumulation: Low potential due to high solubility and rapid metabolism
Soil Mobility: High water solubility can allow migration in moist soils, but ready biodegradability mitigates risk
Other Effects: Large quantities may contribute to nutrient enrichment if released untreated

Disposal Considerations

Disposal Methods: Dispose as non-hazardous chemical waste; no special precautions for landfill or incineration under most regulations
Container Disposal: Rinse with water before recycling or disposing of packaging
Regulatory References: Conform to all local, state, and national regulations for chemical disposal; avoid uncontrolled release to environment

Transport Information

UN Number: Not regulated as a dangerous good
Proper Shipping Name: Choline Chloride
Hazard Class: Not classified
Packing Group: Not assigned
Marine Pollutant: No
Special Transport Precautions: Keep containers well sealed; protect from water and humidity during shipping

Regulatory Information

TSCA: Listed
REACH Registration: Registered, exempt, or not required
OSHA Status: Not hazardous under OSHA Hazard Communication Standard
SARA 302/304/311/312: Not listed
SARA 313: Not subject to reporting
EU Classification: Not classified as hazardous
Other International Inventories: Present on relevant chemical inventories in Canada, Australia, Japan, South Korea, Philippines, New Zealand, China